Pharmaceutical Ingredients

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U.S. FDA Approves Drug Product Containing Lubrizol’s Carbopol® Polymer

Lubrizol is a global producer of high performance pharmaceutical ingredients that have a Pharmaceutical Ingredientsproven track record of use in liquid, semisolid and bioadhesive dosage forms.  Building on our strong foundation in the area of semi-solid products, we have expanded our knowledge and increased our focus on oral solid dosage applications.  more>> 

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Carbopol® polymers are highly efficient gel matrix formers for controlling drug release in solid dosage forms.  Additionally, the polymers provide excellent thickening, suspending and emulsifying properties in semisolid or liquid formulations.

Formulators' Corner

A source for technical tips and ideas to help you explore and apply our technology to your formulations

Question: How does Carbopol® 971P NF polymer differ from Carbopol® 974P NF polymer in controlling drug release?

Answer: Unlike linear hydrophilic polymers, drug release from matrix tablets with Carbopol® polymers is controlled more by the polymer structure than by the viscosity of the polymer. 

Lower viscosity Carbopol® 971P NF polymer is generally more efficient in controlling drug release than highly crosslinked polymers such as Carbopol® 974P NF polymer